发明名称 |
VERFAHREN ZUR HERSTELLUNG VON MIKROVERKAPSELTEN DNS ZUR IMPFUNG UND ZUR GENTHERAPIE |
摘要 |
<p>A method of making a microparticle that contains DNA coding for a polypeptide is described, in which a solvent extraction method is used and solvent extraction takes place at elevated temperature. Oral administration of the microparticle leads to its expression. DNA coding for an immunogen is for stimulating antibody formation in a recipient and DNA coding for a non-immunogenic polypeptide is for gene therapy applications. DNA is incorporated into the microparticle without destruction of its function.</p> |
申请公布号 |
DE69840434(D1) |
申请公布日期 |
2009.02.26 |
申请号 |
DE1998640434 |
申请日期 |
1998.05.15 |
申请人 |
HEALTH PROTECTION AGENCY, SALISBURY |
发明人 |
FARRAR, GRAHAM HENRY;JONES, DAVID HUGH;CLEGG, JAMES CHRISTOPHER |
分类号 |
A61K9/00;C12N15/09;A61K9/16;A61K9/50;A61K9/66;A61K31/70;A61K31/711;A61K39/15;A61K39/165;A61K48/00;C12N15/88 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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