PROTEASE-STABLE, CELL WALL-LYSING ENZYMES

摘要

The present invention relates to a modified polypeptide having the biological activity of lysing bacterial cell walls, the polypeptide containing no caspase, clostripain, enterokinase, factor Xa, granzyme B, Staphylococcus peptidase I (V8 protease), plasmin, streptopain, bacillolysin and/or thrombin cleavage site. The invention further relates to nucleic acids with a sequence coding for the polypeptides of the invention.