发明名称 |
ACACS As Modifiers of the IGF Pathway and Methods of Use |
摘要 |
Human MPTEN genes are identified as modulators of the PTEN pathway, and thus are therapeutic targets for disorders associated with defective PTEN function. Methods for identifying modulators of PTEN, comprising screening for agents that modulate the activity of MPTEN are provided.
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申请公布号 |
US2009053239(A1) |
申请公布日期 |
2009.02.26 |
申请号 |
US20050628575 |
申请日期 |
2005.06.20 |
申请人 |
EXELIXIS, INC. |
发明人 |
MAXWELL MARK E.;OLLMANN MICHAEL MARTIN;HEUER TIMOTHY S.;BJERKE LYNN MARGARET |
分类号 |
A61K39/395;A01K67/027;A61P31/00;C12N5/06;C12Q1/02;C12Q1/68;G01N33/00;G01N33/566 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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