发明名称 COMPOSITION AND METHOD FOR DIAGNOSING AND TREATING LESION ASSOCIATED WITH ANGIOGENESIS
摘要 <P>PROBLEM TO BE SOLVED: To provide a composition and a method for stimulating or inhibiting angiogenesis and/or cardiovascularization in mammals including humans. <P>SOLUTION: The pharmaceutical composition comprises a polypeptide identified as one or more uses thereof, or an antagonist thereto. A new polypeptide, a nucleic acid molecule encoding the polypeptide, a vector and host cell containing the nucleic acid sequence, a chimera polypeptide molecule containing the polypeptide fused with a foreign polypeptide, an antibody binding with the polypeptide, and the method for producing the polypeptide are also provided. <P>COPYRIGHT: (C)2009,JPO&INPIT
申请公布号 JP2009039119(A) 申请公布日期 2009.02.26
申请号 JP20080194764 申请日期 2008.07.29
申请人 GENENTECH INC 发明人 BAKER KEVIN P;FERRARA NAPOLEONE;GERBER HANSPETER;GERRITSEN MARY E;GODDARD AUDREY;GODOWSKI PAUL J;GURNEY AUSTIN L;HILLAN KENNETH J;MARSTERS SCOT A;PAN JAMES;PAONI NICHOLAS F;STEPHAN JEAN-PHILIPPE F;WATANABE COLIN K;WILLIAMS P MICKEY;WOOD WILLIAM I
分类号 C12N15/09;A61K38/00;A61K38/17;A61K39/395;A61K45/00;A61K48/00;A61P9/00;A61P9/04;A61P9/10;A61P9/14;A61P35/00;A61P43/00;C07K14/47;C07K14/475;C07K14/515;C07K16/18;C07K16/22;C07K16/46;C07K19/00;C12N1/19;C12N1/21;C12N5/06;C12N5/10;C12N15/12;C12N15/62;C12P21/02;C12P21/08 主分类号 C12N15/09
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