<p>The invention provides 19-substituted geldanamycin derivatives, pharmaceutically acceptable salts thereof and prodrugs thereof that are potent Hsp90 binding agents useful for the treatment of, and/or the amelioration of symptoms of, cancer and other proliferative tissue disorders.</p>
申请公布号
WO2009026548(A1)
申请公布日期
2009.02.26
申请号
WO2008US74077
申请日期
2008.08.22
申请人
THE REGENTS OF THE UNIVERSITY OF COLORADO;ROSS, DAVID;SIEGEL, DAVID;GUO, WENCHANG;MOODY, CHRISTOPHER, J.;MCERLEAN, CHRISTOPHER, S.P.