发明名称 CRYSTAL FORMS OF SAXAGLIPTIN AND PROCESSES FOR PREPARING SAME
摘要 Physical crystal structures of a compound of the formula I: are provided including the free base monohydrate thereof (form H-1) and the hydrochloric acid salt thereof, including hydrochloric acid salt containing 0.75 equivalent of H2O (form H0.75-3) and hydrochloric acid salt containing 2 equivalents of H2O (form H2-1), and hydrochloric acid salt Pattern P-5, preferably in substantially pure form, and other forms as described herein, pharmaceutical compositions containing structures of compound I or IA, processes for preparing same, intermediates used in preparing same, and methods of treating diseases such as diabetes using such structures.
申请公布号 US2009054303(A1) 申请公布日期 2009.02.26
申请号 US20080105316 申请日期 2008.04.18
申请人 BRISTOL-MYERS SQUIBB COMPANY 发明人 GOUGOUTAS JACK Z.;MALLEY MARY F.;DIMARCO JOHN D.;YIN XIAOTIAN S.;WEI CHENKOU;YU JURONG;VU TRUC CHI;JONES GREGORY SCOTT;SAVAGE SCOTT A.
分类号 A61K38/28;A61K31/403;A61K38/17;A61P3/04;C07D209/52 主分类号 A61K38/28
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