| 发明名称 |
NAPHTHYLPYRIMIDINE, NAPHTHYLPYRAZINE AND NAPHTHYLPYRIDAZINE ANALOGS AND THEIR USE AS AGONISTS OF THE WNT-BETA-CATENIN CELLULAR MESSAGING SYSTEM |
| 摘要 |
The present invention relates to naphthylpyrimidine analogs, methods of making naphthylpyrimidine analogs, compositions comprising a naphthylpyrimidine analog, and methods for treating canonical Wnt-beta-catenin cellular messaging system-related disorders comprising administering to a subject in need thereof an effective amount of a naphthylpyrimidine, naphthylpyrazine and naphthylpyridazine analog.
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| 申请公布号 |
US2009054392(A1) |
申请公布日期 |
2009.02.26 |
| 申请号 |
US20080194235 |
申请日期 |
2008.08.19 |
| 申请人 |
WYETH |
发明人 |
PELLETIER JEFFREY CLAUDE;FELIX LUCIANA DE ARAUJO;GREEN DANIEL MICHAEL;HAUZE DIANE BARBARA;LUNDQUIST, IV JOSEPH THEODORE;MANN CHARLES WILLIAM;MEHLMANN JOHN FRANCIS;ROGERS, JR. JOHN FRANCIS;VERA MATTHEW DOUGLAS;MOLINARI ALBERT JOHN |
| 分类号 |
A61K31/397;A61K31/496;A61K31/505;A61K31/5377;A61K31/55;A61K31/551;A61P19/08;A61P25/28;A61P35/00;C07D239/24;C07D243/08;C07D403/02;C07D413/14 |
主分类号 |
A61K31/397 |
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