发明名称 |
A NOVEL DIAGNOSTIC SENSOR FOR RAPID AND REPRODUCIBLE RO52 PROTEIN DOMAIN DETECTION |
摘要 |
The present invention relates to the use of specific synthetic sensor molecules for the discrimination of proteins and protein domains involved in autoimmunity. More specifically, in one embodiment, the invention relates to the detection of antibodies which bind to specific domains of the Ro52 protein. In another embodiment, the invention relates to the use of specific synthetic sensor molecules to identify domains of the Ro52 protein with different antibody specificities. The invention also includes a method for assessing the risk that a fetus will develop congenital heart block. The invention enables the evaluation and differential diagnosis of a range of autoimmune disorders, allowing appropriate treatment or more generally medical intervention decisions to be made. |
申请公布号 |
WO2008114152(A3) |
申请公布日期 |
2009.02.26 |
申请号 |
WO2008IB01470 |
申请日期 |
2008.03.21 |
申请人 |
MEADOWLAND BUSINESS PARTNERS AB;WINQVIST, OLA;WAHREN-HERLENIUS, MARIE;BALTZER, LARS |
发明人 |
WINQVIST, OLA;WAHREN-HERLENIUS, MARIE;BALTZER, LARS |
分类号 |
G01N33/68 |
主分类号 |
G01N33/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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