发明名称 NOVEL PREPARATION FOR EXTERNAL USE
摘要 A compound represented by the formula (I), salt thereof, or hydrate thereof has an excellent anti-pruritic effect and an excellent effect in terms of metabolism. The topical formulation of the present invention has excellent skin absorption properties of the compound represented by the formula (I), salt thereof, or hydrate thereof. Furthermore, the topical formulation of the present invention is excellent in stability because ingredients are hardly bled after long-term storage. (see formula I) wherein R represents hydroxyl, C1-6 alkoxy optionally substituted with C1-6 alkoxy, or amino optionally substituted with C1-6 alkyl.
申请公布号 CA2696793(A1) 申请公布日期 2009.02.26
申请号 CA20082696793 申请日期 2008.08.15
申请人 EISAI R&D MANAGEMENT CO., LTD. 发明人 KIMURA, CHIHARU;SAKURAI, MAHO
分类号 C07D239/84;A61K9/06;A61K31/517;A61K47/12;A61K47/14;A61K47/34;A61K47/44;A61P17/00;A61P17/04;A61P37/08;A61P43/00 主分类号 C07D239/84
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