发明名称 |
USE OF HPPD INHIBITORS IN THE TREATMENT OF DEPRESSION AND/OR WITHDRAWAL SYMPTOMS ASSOCIATED WITH ADDICTIVE DRUGS. |
摘要 |
<p>The present invention relates to, inter alia , the use of a compound capable of inhibiting 4-hydroxyphenylpyruvate dioxygenase (HPPD) in an animal in the manufacture of a medicament for use in the treatment and/or prevention of depression. The invention also provides for the use of a compound capable of inhibiting HPPD in an animal in the manufacture of a medicament for use in the treatment of the withdrawal symptoms associated with an addictive drug which causes dopamine dependant associative learning disorders in said animal. In a particular embodiment said HPPD inhibitor is selected from the group consisting of the compound depicted as compound 1; 2; and 3.22.</p> |
申请公布号 |
MX2009001710(A) |
申请公布日期 |
2009.02.25 |
申请号 |
MX20090001710 |
申请日期 |
2006.08.18 |
申请人 |
SYNGENTA LIMITED |
发明人 |
KIM ZACHARY TRAVIS;JOHN POSNER |
分类号 |
A61K31/4412;A61K31/00;A61K31/122;A61K31/277;A61K31/341;A61K31/357;A61K31/415;A61K31/4155;A61K31/42;A61K31/422;A61K31/44;A61K31/4439;A61K45/06;A61P25/24;A61P25/30 |
主分类号 |
A61K31/4412 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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