发明名称 |
PHARMACEUTICAL AND COSMETIC USE OF SILICA |
摘要 |
The invention provides the use of silica for cosmetic and/or medical treatment of skin, including improving and enhancing the skin-barrier, anti-aging treatment and photo-protective treatment. The invention is based on the finding that silica exhibits a multi-faceted biological effect useful in the cosmetic and/or therapeutic treatment of skin for the above purposes. Specifically, it has been shown that silica induces markers (involucrin, filaggrin and transglutaminase-1) for skin barrier formation in keratinocytes, induces collagen expression in dermal fibroblasts and inhibits UVA-induced up-regulation of photo-aging markers (matrix metalloproteinase MMP-1 and cytokine IL-6). |
申请公布号 |
EP2026880(A1) |
申请公布日期 |
2009.02.25 |
申请号 |
EP20070736621 |
申请日期 |
2007.05.07 |
申请人 |
BLAA LONID HF. |
发明人 |
EINARSSON, SIGURBJORN;BRYNJOLFSDOTTIR, ASA;KRUTMANN, JEAN |
分类号 |
A61Q17/00;A61K8/00;A61K8/25;A61K9/00;A61K33/00;A61Q17/04;A61Q19/00;A61Q19/08 |
主分类号 |
A61Q17/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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