发明名称 |
High-molecular weight derivatives of camptothecins |
摘要 |
It is intended to provide water-soluble derivative of camptothecins which are excellent in therapeutic effect and suitable for chemotherapy for cancer. Namely, a water-soluble high-molecular weight derivative of camptothencins being excellent in sustained-release which is obtained by ester-bonding a carboxylic acid group of a polyethylene glycol-polycarboxylic acid polymer to a phenolic hydroxyl group of phenolic camptothencins.
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申请公布号 |
US7495099(B2) |
申请公布日期 |
2009.02.24 |
申请号 |
US20050532670 |
申请日期 |
2005.06.16 |
申请人 |
NIPPON KAYAKU KABUSHIKI KAISHA |
发明人 |
KITAGAWA MASAYUKI;OKAMOTO KAZUYA |
分类号 |
C07D491/22;A61K31/4745;A61K47/48;A61P35/00;A61P43/00 |
主分类号 |
C07D491/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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