发明名称 |
8-(3-amino-piperidin-1-yl)-7-(but-2-ynyl)-xanthines, the preparation thereof and their use as pharmaceutical compositions |
摘要 |
The application relates to new substituted xanthines of general formula wherein R1 and R2 are defined as in claims 1 to 11, the tautomers, the enantiomers, the diastereomers, the mixtures thereof and the salts thereof, which have valuable pharmacological properties, particularly an inhibiting effect on the activity of the enzyme dipeptidylpeptidase-IV (DPP-IV).
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申请公布号 |
US7495003(B2) |
申请公布日期 |
2009.02.24 |
申请号 |
US20050218057 |
申请日期 |
2005.09.01 |
申请人 |
BOEHRINGER INGELHEIM INTERNATIONAL GMBH |
发明人 |
ECKHARDT MATTHIAS;HIMMELSBACH FRANK;LANGKOPF ELKE;TADAYYON MOHAMMAD;THOMAS LEO |
分类号 |
C07D473/06;A61K31/522;A61P3/10;C07D473/04;C07D519/00 |
主分类号 |
C07D473/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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