发明名称 |
Immunizing composition and method for inducing an immune response against the beta-secretase cleavage site of amyloid precursor protein |
摘要 |
The present invention is directed to an immunizing composition containing an antigenic product such as a multiple antigen peptide system (MAPS) or a filamentous bacteriophage displaying an AbetaPP epitope spanning the beta-secretase cleavage site of AbetaPP and a method for inducing an immune response against the beta-secretase cleavage site of AbetaPP using this immunizing composition. The present invention is also directed to antibodies against the beta-secretase cleavage site of AbetaPP and their use in a method for inhibiting the formation of amyloid beta.
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申请公布号 |
US7494655(B2) |
申请公布日期 |
2009.02.24 |
申请号 |
US20040506665 |
申请日期 |
2004.09.07 |
申请人 |
RAMOT AT TEL-AVIV UNIVERSITY LTD. |
发明人 |
SOLOMON BEKA |
分类号 |
A61K9/127;A61K39/00;A61K39/385;A61K39/39;A61K39/395;A61P25/28;A61P37/04;C07H21/04;C07K7/06;C07K14/47;C07K16/18;C12N1/21;C12N15/09 |
主分类号 |
A61K9/127 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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