МОДИФИЦИРОВАННЫЕ 5'-ФОСФОРНАТЫ 2',3'-ДИДЕЗОКСИ-3'-ТИАЦИТИДИНА - ПОТЕНЦИАЛЬНЫЕ ПРОТИВОВИРУСНЫЕ ПРЕПАРАТЫ

摘要

FIELD: chemistry. ^ SUBSTANCE: invention relates to 5'-phosphorus-containing derivatives of 2',3'-dideoxy-3'-thiacytidine with general structural formula given below , where R=H, NH2-C(O)-. The invented compounds can be used for inhibiting reproduction of the human immunodeficiency virus type 1 in an MT-4 cell culture. ^ EFFECT: increased antiviral activity of the compounds. ^ 1 cl, 2 tbl, 4 ex