发明名称 |
16-{2-BENZOYLAMINO-2-[(3,5-DI-TRET-BUTHYL-4-HYDROXUPHENYL)ALKYL-CARBAMOYL]VINYL}-LABDATRIENS WITH ANTIOXIDANT, HEPATOPROTECTION AND HEMOSTIMULATING EFFECT |
摘要 |
FIELD: chemistry. ^ SUBSTANCE: invention concerns new compounds, particularly 16-{2-benzoylamino-2- [(3,5-di-tet-buthyl-4-hydroxyphenyl)-alkylcarbamoyl]vinyl}-labdatriens of the formula (I) with antioxidant, hepatoprotection and hemostimulating effect, allowing for application under toxic hepatitis and in correction of side effects of cytostatic medicines (e.g. cyclophosphane). Compounds of the formula 1 are obtained from raw plant material, Siberian cedar needles or oleo-resin. ^ EFFECT: obtaining compounds with antioxidant, hepatoprotection and hemostimulating effect. ^ 4 tbl, 5 ex |
申请公布号 |
RU2346940(C1) |
申请公布日期 |
2009.02.20 |
申请号 |
RU20070132038 |
申请日期 |
2007.08.23 |
申请人 |
NOVOSIBIRSKIJ INSTITUT ORGANICHESKOJ KHIMII IM. N.N. VOROZHTSOVA SIBIRSKOGO OTDELENIJA ROSSIJSKOJ AKADEMII NAUK (NIOKH SO RAN) (STATUS GOSUDARSTVENNOGO UCHREZHDENIJA) |
发明人 |
KHARITONOV JURIJ VIKTOROVICH;SHUL'TS EHL'VIRA EHDUARDOVNA;SOROKINA IRINA VASIL'EVNA;TOLSTIKOVA TAT'JANA GENRIKHOVNA;BAEV DMITRIJ SERGEEVICH;ZHUKOVA NATAL'JA ANATOL'EVNA;TOLSTIKOV GENRIKH ALEKSANDROVICH |
分类号 |
C07D307/52;A61K31/341;A61P1/16 |
主分类号 |
C07D307/52 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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