发明名称 SYNERGETIC COMBINATIONS CONTAINING RENIN INHIBITOR AND INTENDED FOR TREATMENT OF CARDIOVASCULAR DISEASES
摘要 FIELD: medicine; pharmacology. ^ SUBSTANCE: invention refers to pharmaceutical combination of antihypertensive action rennin inhibitor in effective amount of formula or its pharmaceutically acceptable salt and, at least, one therapeutic agent chosen from group, including (II) HmG-CoA-reductase inhibitor or its pharmaceutically acceptable salt, (IV) calcium channel-blocking agent or its pharmaceutically acceptable salt, (V) aldosteronsynthase inhibitor or its pharmaceutically acceptable salt and (IX) diuretic or its pharmaceutically acceptable salt, and the carrier. Besides, discovered is method of prevention, delayed development, treatment of disease or condition and application of combination for preparation of medical product. ^ EFFECT: combinations under the invention manifest synergetic therapeutic action. ^ 10 cl, 16 ex
申请公布号 RU2346703(C2) 申请公布日期 2009.02.20
申请号 RU20060132668 申请日期 2006.09.12
申请人 NOVARTIS AG 发明人 KHEUITT UILL'JAM;VASELLA DAE'EL' LUSI;UEHBB RANDI LI
分类号 A61K45/00;A61K45/06;A61K31/165;A61K31/405;A61K31/41;A61K31/437;A61K31/4422;A61K31/47;A61K31/506;A61K31/549;A61K31/55;A61K31/554;A61K31/585;A61K31/64;A61P3/04;A61P3/06;A61P3/10;A61P5/06;A61P7/10;A61P9/00;A61P9/04;A61P9/10;A61P9/12;A61P13/12;A61P19/04;A61P27/06;A61P43/00 主分类号 A61K45/00
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