发明名称 Compositions and methods for indentifying transforming and tumor suppressor genes
摘要 Provided herein are nucleic acids, proteins, vectors, cells, kits, devices and methods useful for identifying regulatable proteins that are able to complement components of cellular signaling pathways. Also provided are compositions and methods using these complementing genes directly as markers for cancer diagnosis or prognosis and as targets for anti-neoplastic therapeutics. Further provided are methods for using changes caused by expression of the complementing genes to indirectly identify associated genes to be used as markers for cancer diagnosis or prognosis and as targets for anti-neoplastic therapeutics.
申请公布号 US2009047675(A1) 申请公布日期 2009.02.19
申请号 US20080150941 申请日期 2008.05.01
申请人 DANA-FARBER CANCER INSTITUTE, INC. 发明人 ROBERTS THOMAS M.;ZHAO JEAN;HILL DAVID E.;HAHN WILLIAM C.;BOEHM JESSE
分类号 C12N5/06;C12Q1/68 主分类号 C12N5/06
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