CELL-BASED COMPOSITIONS AND METHOD FOR TREATING CONDITIONS OF THE NERVOUS SYSTEM
摘要
Disclosed herein are cell-based compositions for the treatment of conditions of the nervous system and methods for their use. In one embodiment, a cell-based composition comprises glial-restricted progenitors (GRPs) genetically modified to express a targeting ligand on their cell surface. Methods for the preparation of such cell-based compositions are disclosed. Also disclosed is a method for treating a subject suffering from a condition of the central nervous system by providing therapeutic cells (e.g., GRPs) through an intra-arterial route of administration.
申请公布号
WO2009023795(A2)
申请公布日期
2009.02.19
申请号
WO2008US73209
申请日期
2008.08.14
申请人
THE JOHNS HOPKINS UNIVERSITY;KERR, DOUGLAS, A.;GORELIK, MICHAEL;LEVY, MICHAEL