| 摘要 |
Specific binding peptides having a general schematized structure of an op tional N-terminal hinge region joined to an immunoglobulin-derived constant sub-region comprising a CH2 region and a CH3 region, followed by a PIMS link er peptide and at least one specific binding domain are provided, along with encoding nucleic acids, vectors and host cells. Also provided are methods f or making such peptides and methods for using such peptides to treat or prev ent a variety of diseases, disorders or conditions, as well as to ameliorate at least one symptom associated with such a disease, disorder or condition. |
