METHODS OF MODULATING MESENCHYMAL STEM CELL DIFFERENTIATION

摘要

The present disclosure includes compositions and methods for modulating the differentiation of cells having osteogenic differentiation potential (such as mesenchymal stem cells (MSCs)) towards the osteogenic fate, and for obtaining diagnostic and prognostic information relating to diseases and disorders characterized by defects in osteogenic differentiation. The compositions include miRNAs, rm'RNA mimics, miRNA inhibitors, and siRNAs.