NEW YEAST STRAIN HAVING HIGH PRODUCTIVITY OF S-ADENOSYLMETHIONINE AND METHOD FOR PRODUCING THE SAME

摘要

PROBLEM TO BE SOLVED: To provide a new yeast strain capable of safely producing a large quantity of AdoMet and a method for producing the new yeast strain.

SOLUTION: The invention provides a yeast having a mutant S-adenosylhomocysteine hydrolase gene introduced by a self cloning method. The mutant gene codes a protein having an amino acid sequence obtained by the substitution, deletion, insertion and/or addition of one or more amino acids in the amino acid sequence shown by the sequence No.2. The protein has lowered S-adenosylhomocysteine hydrolysis activity compared with the protein having the amino acid sequence shown by the sequence No.2.

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