发明名称 |
Octahydropyrano[3,4-C]Pyrrole Tachykinin Receptor Antagonists |
摘要 |
The present invention is directed to certain hydropyranopyrrolidine compounds which are useful as neurokinin-1 (NK-1) receptor antagonists, and inhibitors of tachykinin and in particular substance P. The invention is also concerned with pharmaceutical formulations comprising these compounds as active ingredients and the use of the compounds and their formulations in the treatment of certain disorders, including emesis, urinary incontinence, depression, and anxiety.
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申请公布号 |
US2009048248(A1) |
申请公布日期 |
2009.02.19 |
申请号 |
US20060086810 |
申请日期 |
2006.12.18 |
申请人 |
DEVITA ROBERT J;BAO JIANMING;MILLS SANDER G |
发明人 |
DEVITA ROBERT J.;BAO JIANMING;MILLS SANDER G. |
分类号 |
A61K31/407;A61K31/4196;A61K31/422;A61K31/427;A61K31/4439;A61K31/497;A61K31/506;A61K31/5377;C07D491/052 |
主分类号 |
A61K31/407 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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