发明名称 METHOD OF TREATING STRESS-MEDIATED DEPRESSION
摘要 The present invention relates to a method for the treatment of depression comprising administering a therapeutically effective amount of gaboxadol to a patient, wherein the level of one or more inflammatory markers in said patient is increased or abnormal. The present invention also relates to a method for the treatment of stress-mediated depression comprising administering a therapeutically effective amount of gaboxadol to a patient, wherein the level of one or more inflammatory markers is increased or abnormal in said patient. The present invention also relates to a method for the treatment of depression or the amelioration of one or more depressive symptoms comprising administering a therapeutically effective amount of gaboxadol to a patient, wherein the clinical presentation of one or more symptoms of depression are the physiological effect of a general medical condition. Furthermore the present also relates to a method for testing the therapeutic effectiveness of a compound in the treatment of depression or reducing the symptoms of depression comprising measuring the amount of one or more inflammatory markers in a sample from a patient before said compound is administered to the patient and comparing with the amount of said one or more inflammatory markers in a sample from the same patient after administration of said compound to the patient.
申请公布号 US2009048288(A1) 申请公布日期 2009.02.19
申请号 US20080187865 申请日期 2008.08.07
申请人 H. LUNDBECK A/S 发明人 EBERT BJARKE;MADSEN TORSTEN MELDGAARD
分类号 A61K31/437;A61P25/00;A61P25/24;C12Q1/28;C12Q1/37;C12Q1/52;G01N33/68 主分类号 A61K31/437
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