发明名称 SUBSTITUTED SPIROCYCLIC CGRP RECEPTOR ANTAGONISTS
摘要 I (wherein variables A1, A2, A3, A4, M, N, J, Q, R4, Ea, Eb, Ec, R6, R7, Re, Rf, RPG and Y are as described herein) which are antagonists of CGRP receptors and which are useful in the treatment or prevention of diseases in which the CGRP is involved, such as migraine. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
申请公布号 KR20090018107(A) 申请公布日期 2009.02.19
申请号 KR20087029977 申请日期 2008.12.08
申请人 MERCK & CO., INC. 发明人 WOOD MICHAEL R.;BELL IAN M.;GALLICCHIO STEVEN N.;SELNICK HAROLD G.;STUMP CRAIG A.;ZARTMAN C. BLAIR
分类号 C07D401/12;A61K31/403;C07D413/12;C07D471/20 主分类号 C07D401/12
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