ISOLATION OF ANTI-DESMOGLEIN 1 ANTIBODIES BY PHAGE DISPLAY OF PEMPHIGUS FOLIACEUS AUTOANTIBODIES
摘要
This invention relates to compositions and methods for the use of anti- autoimmune reagents that specifically bind to anti-desmoglein antibodies, which are responsible for pemphigus foliaceus. In addition, the invention relates to methods and compositions for inhibiting the expression or function of a variable region of an anti- desmoglein (anti-Dsg) pathogenic autoantibody.
申请公布号
WO2009002380(A3)
申请公布日期
2009.02.19
申请号
WO2008US05924
申请日期
2008.05.09
申请人
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA;PAYNE, AIMEE, S.;STANLEY, JOHN, R.;SIEGEL, DONALD, L.;YAMAGAMI, JUN;ISHII, KEN
发明人
PAYNE, AIMEE, S.;STANLEY, JOHN, R.;SIEGEL, DONALD, L.;YAMAGAMI, JUN;ISHII, KEN