Regulators of MMP-9 and uses therof

摘要

A method of regulating an activity of metalloproteinase 9 (MMP-9) is disclosed. The method comprises containing the MMP-9 with an agent which specifically interacts with an OG domain of the MMP-9. Molecules capable of specifically interacting with the OG domain, methods of identifying same, pharmaceutical compositions comprising same and uses thereof are also disclosed.