发明名称 |
IMPROVED MICROBIAL PRODUCTION OF INDIGO |
摘要 |
There is provided an improved process for the biosynthetic production of indigo, the improvement comprising removing unwanted by-products such as isatin or indirubin from the broth in which such indigo is produced. Isatin can be removed by enzymatic activity using an isatin-removing enzyme such as an isatin hydrolase, or by other technique s such as process parameters (elevated temperature, pH), or by contacting the broth containing the isatin with appropriate adsorption compounds/compositions such as carbon or appropriate resins. Since isatin is the precursor of indirubin, the indirubin levels are decreased as a result of isatin removal. |
申请公布号 |
CA2235590(C) |
申请公布日期 |
2009.02.17 |
申请号 |
CA19962235590 |
申请日期 |
1996.11.19 |
申请人 |
GENENCOR INTERNATIONAL, INC. |
发明人 |
WENDT, DAN J.;WEYLER, WALTER;LAUFF, JOHN J.;DODGE, TIMOTHY C. |
分类号 |
C12N15/09;C12N15/55;C09B7/00;C12N1/21;C12N9/02;C12N9/86;C12N15/52;C12N15/53;C12N15/63;C12P17/10;C12P17/16;C12P17/18;C12R1/19;H04W24/00;H04W84/14 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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