发明名称 |
Alpha-ketoamide derivative, and production method and use thereof |
摘要 |
The present invention provides a compound represented by the formula (I): (wherein R1 is a lower alkyl substituted by a lower alkoxy or a heterocyclic group, or a heterocyclic group; R2 is a lower alkyl optionally substituted by a phenyl; and R3 is a lower alkyl optionally substituted by a halogen, a lower alkoxy or a phenyl, or a fused polycyclic hydrocarbon group), which is well absorbed orally, exhibits durability of good blood level and has potent calpain inhibitory activity.
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申请公布号 |
US7491705(B2) |
申请公布日期 |
2009.02.17 |
申请号 |
US20040582015 |
申请日期 |
2004.12.08 |
申请人 |
SENJU PHARMACEUTICAL CO., LTD. |
发明人 |
SHIRASAKI YOSHIHISA;MIYASHITA HIROYUKI;NAKAMURA MASAYUKI;INOUE JUN |
分类号 |
A61K38/05;C07C271/22;C07C275/16;C07C317/40;C07D213/30;C07D295/215;C07D307/20;C07D309/12;C07K5/02 |
主分类号 |
A61K38/05 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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