发明名称 |
PROCESS FOR THE PREPARATION OF BISPHOSPHINES |
摘要 |
A method of manufacturing a compound of general formula (R3-C)2P-L1-X-L2-P-{ C- R3)2, in which each R is independently a pendant, optionally substituted, organic group through which the group is linked to tertiary carbon atom C; L1, L2 are independently a linking group selected from an optionally substituted lower alkylene chain connecting the respective phosphorus atom to the group X and X is a bridging group comprising an optionally substituted aryl moiety to which the phosphorus atoms are linked on available adjacent carbon atoms, comprises: i) reacting together a compound of formula H- LI-X-L2-H with an organometallic compound to form an intermediate compound of formula M-L1-X-L2-M, where M is an alkali metal atom; ii) reacting said intermediate compound with a compound of formula (R3-C)2P-A, where A is a halogen atom, to form said compound of general formula (R3-C)2P-L1-X-L2-P-(C-R3)2. M is preferably lithium, potassium or sodium and the intermediate compound m ay be isolated or not. The reaction (i) may advantageously be carried out in the presence of a complexing agent such as tetramethyethylenediamine.
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申请公布号 |
CA2323906(C) |
申请公布日期 |
2009.02.17 |
申请号 |
CA19992323906 |
申请日期 |
1999.03.16 |
申请人 |
INEOS ACRYLICS UK LIMITED |
发明人 |
CAMPBELL, RICHARD ANTHONY;NEWMAN, PAUL DAVID;TOOZE, ROBERT PAUL;EASTHAM, GRAHAM RONALD;EDWARDS, PETER GERALD;THORPE, JAMIE MICHAEL |
分类号 |
C07F9/50;B01J31/24;C07C51/14;C07C67/38 |
主分类号 |
C07F9/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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