| 发明名称 |
DETECTION AND USE OF ANTIVIRAL RESISTANCE MUTATIONS |
| 摘要 |
<p>The present invention relates generally to viral variants exhibiting reduced sensitivity to particular agents and/or reduced interactivity with immunological reagents. More particularly, the present invention is directed to hepatitis B virus (HBV) variants exhibiting complete or partial resistance to nucleoside or nucleotide analogs and/or reduced interactivity with antibodies to viral surface components including reduced sensitivity to these antibodies. Vaccines and diagnostic assays are also contemplated herein.</p> |
| 申请公布号 |
KR20090016632(A) |
申请公布日期 |
2009.02.16 |
| 申请号 |
KR20097000212 |
申请日期 |
2007.06.04 |
| 申请人 |
MELBOURNE HEALTH;AUSTIN HEALTH;BAYSIDE HEALTH;SOUTHERN HEALTH;ST. VINCENT'S HOSPITAL(MELBOURNE) LTD. TRADING ASST. VINCENT'S HOSPITAL MELBOURNE |
发明人 |
BARTHOLOMEUSZ ANGELINE INGRID;LOCARNINI STEPHEN;AYRES ANNA;YUEN LILLY KA WAI;ANGUS PETER WILLIAM;SASADEUSZ JOSEPH JOHN;DESMOND PAUL;TILLMAN HANS;BOCK THOMAS;SIEVERT WILLIAM;LEWIN SHARON |
| 分类号 |
C12N15/51;C12N7/00;C12Q1/70 |
主分类号 |
C12N15/51 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
