发明名称 N-(AMINOHETEROARYL)-1H-INDOLE-2-CARBOXAMIDE DERIVATIVES, AND PREPARATION AND THERAPEUTIC APPLICATION THEREOF.
摘要 <p>The invention concerns compounds of general formula (I) : wherein Z 1 , Z 2 , Z 3 , and Z 4 represent, independently of one another, a nitrogen atom or a C(R 6 ) group, at least one of which corresponds to a nitrogen atom and at least one of which corresponds to a C(R 6 ) group, n is equal to 0, 1, 2 or 3, Y represents an optionally substituted aryl or heteroaryl, and Z represents a cyclic amine bound by the nitrogen atom of formula , in the base or acid addition salt state, and in the hydrate or solvate state. The invention also concerns a preparation method and a therapeutic application.</p>
申请公布号 MX2009001222(A) 申请公布日期 2009.02.13
申请号 MX20090001222 申请日期 2007.07.30
申请人 SANOFI-AVENTIS 发明人 LAURENT DUBOIS;YANNICK EVANNO;ANDRE MALANDA;CATHERINE GILLE;DAVID MACHNIK
分类号 C07D401/14;A61K31/4439;A61P3/10;A61P11/00;A61P13/00;A61P15/00;A61P17/00;A61P25/04;A61P25/24;A61P29/00;C07D213/74;C07D401/04;C07D401/12;C07D403/12 主分类号 C07D401/14
代理机构 代理人
主权项
地址