发明名称 ATM INHIBITORS
摘要 A compound of formula I: and isomers, salts, solvates, chemically protected forms, and prodrugs thereof, wherein: R1 and R2 together form, along with the nitrogen atom to which they are attached, an optionally substituted heterocyclic ring having from 4 to 8 ring atoms; and RN1 is selected from hydrogen, an optionally substituted C1-7 alkyl group, an optionally substituted C3-20 heterocyclyl group, an optionally substituted C5-20 aryl group, an acyl group, an ester group and an amido group, and its use as a pharmaceutical.
申请公布号 US2009043091(A1) 申请公布日期 2009.02.12
申请号 US20080233736 申请日期 2008.09.19
申请人 KUDOS PHARMACEUTICALS LIMITED 发明人 SMITH GRAEME CAMERON MURRAY;MARTIN NIALL MORRISON BARR;COCKCROFT XIAO-LING FAN;MATTHEWS IAN TIMOTHY WILLIAMS;MENEAR KEITH ALLAN;RIGOREAU LAURENT JEAN MARTIN;HUMMERSONE MARC GEOFFREY;GRIFFIN ROGER JOHN
分类号 C07D243/08;A61P31/12;A61P35/00;C07D223/02;C07D279/18;C07D409/04;C07D409/14;C07D413/04;C07D413/14;C07D417/04;C07D417/14;C07D491/04;C07D495/04 主分类号 C07D243/08
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