| 发明名称 |
DETECTION OF SUB-CELLULAR COMPARTMENT LOCALIZATION OF A MOLECULE USING A REDUCED AFFINITY ENZYME COMPLEMENTATION REPORTER SYSTEM |
| 摘要 |
Methods and compositions for detecting the sub-cellular localization of a molecule are provided. Aspects of the invention include detecting translocation of a cell-surface receptor to a sub-cellular compartment, e.g., the endosome, using a reduced affinity enzyme complementation reporter system. Also provided are systems and kits for use in practicing embodiments of the methods. |
| 申请公布号 |
WO2008085481(A3) |
申请公布日期 |
2009.02.12 |
| 申请号 |
WO2007US26344 |
申请日期 |
2007.12.26 |
| 申请人 |
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY;BLAU, HELEN M.;HAMMER, MARK, MORRIS;WEHRMAN, TOM |
发明人 |
BLAU, HELEN M.;HAMMER, MARK, MORRIS;WEHRMAN, TOM |
| 分类号 |
C12Q1/00;C12Q1/68;C12Q1/70;G01N33/53 |
主分类号 |
C12Q1/00 |
| 代理机构 |
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