摘要 |
This invention provides fused heterocycles having the formula: in which R1 is a member selected from the group consisting of H, substituted or unsubstituted arylalkyl and substituted or unsubstituted heteroarylalkyl. R2 is a member selected from the group consisting of H substituted or unsubstituted alkenyl, substituted or unsubstituted arylalkyl and substituted or unsubstituted heteroarylalkyl. R3 is a member selected from the group consisting of H1 C1-C6 substituted or unsubstituted alkyl, substituted or unsubstituted arylalkyl and substituted or unsubstituted heteroarylalkyl. R4 is a member selected from OH and O- X+, in which X+ is positive ion which is a member selected from organic positive ions and inorganic positive ions. Substituted or unsubstituted arylalkyl and substituted or unsubstituted heteroarylalkyl moieties have the formula: in which Ar is a member selected from the group consisting of substituted or unsubstituted aryl and substituted or unsubstituted heteroaryl. The index n is an integer from 1 to 4. Formulae A, B. |
申请人 |
SEPRACOR INC.;HEFFERNAN, MICHELE, L.R.;DORSEY, JAMES, M.;FANG, QUN, KEVIN;FOGLESONG, ROBERT, J.;HOPKINS, SETH, C.;OGBU, CYPRIAN, O.;SOUKRI, MUSTAPHA;SPEAR, KERRY, L. |
发明人 |
HEFFERNAN, MICHELE, L.R.;DORSEY, JAMES, M.;FANG, QUN, KEVIN;FOGLESONG, ROBERT, J.;HOPKINS, SETH, C.;OGBU, CYPRIAN, O.;SOUKRI, MUSTAPHA;SPEAR, KERRY, L. |