MODIFIED BACTERIOPHAGE INCLUDING AN ALPHA/BETA SMALL ACID-SOLUBLE SPORE PROTEIN (SASP) GENE

摘要

Provided is a modified bacteriophage capable of infecting a target bacterium, which bacteriophage includes an a/ß small acid-soluble spore protein (SASP) gene encoding a SASP which is toxic to the target bacterium, wherein the SASP gene is under the control of a constitutive promoter which is foreign to the bacteriophage and the SASP gene.