发明名称 |
Detecting disease association with aberrant glycogen synthase kinase 3beta expression |
摘要 |
The present invention provides a method for diagnosing a disease or disorder associated with aberrant GSK-3beta expression and/or activity or for determining the predisposition of a subject to the disease or disorder. In particular, the methods of the present invention comprise detecting a marker that comprises one or more polymorphisms and/or one or more allelic variants of a glycogen synthase kinase 3beta gene. The present invention also relates to a method for identifying new markers that are diagnostic of a disease or disorder associated with aberrant GSK-3beta expression and/or activity. Furthermore, the present invention relates to methods of identifying and producing candidate compounds for the treatment of a disease or disorder associated with aberrant GSK-3beta expression and/or activity. |
申请公布号 |
US2009041862(A1) |
申请公布日期 |
2009.02.12 |
申请号 |
US20050579796 |
申请日期 |
2005.05.06 |
申请人 |
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发明人 |
SCHOFIELD PETER ROBERT;KWOK JOHN BING JEE |
分类号 |
A61K33/00;C07H21/04;C12N9/12;C12N15/52;C12Q1/48;C12Q1/68;G01N33/573 |
主分类号 |
A61K33/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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