| 摘要 |
A coated alpha-lipoic acid particle is provided to efficiently suppress the smell of alpha-lipoic acid, improve stability of alpha-lipoic acid, and stably apply to the aqueous composition by using the material forming ionic bond with alpha-lipoic acid and water-insoluble polymer as coating material. The coated alpha-lipoic acid particle comprises the alpha-lipoic acid core and a first coating layer which is formed on the alpha-lipoic acid core and contains the microparticle selected from arginine, cystine, lysine, tryptophan, cysteine, polyethyleneimine, polyvinylpyrrolidone, quaternary ammonium polymethylmethacrylate, polyacrylic acid, polyacrylic acid metal salt, chitosan, gelatin, hyaluronic acid, alginic acid, alginic acid metal salt, starch, oxidized starch, cellulose, cellulose acetate, carboxymethyl cellulose and metal hydroxide.
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