Antibody compositions specific for lgE, lgG4 and lgA epitopes as tools for the design of hypoallergenic molecules for specific immunotherapy

摘要

The invention relates to a composition comprising recombinant antibodies capable of binding to epitopes recognized by antibodies of a specific isotype, in particular, human IgE, IgG4 and/or IgA antibodies, a method of obtaining such a composition and the use of individual antibodies of such a composition as tools for the design of hypoallergenic molecules for specific immunotherapy, as well as a method for generating such hypoallergenic molecules.