发明名称 |
TREATMENT OF CELL-MEDIATED IMMUNE DISEASES |
摘要 |
9-cis retinoic acid and pharmaceutically acceptable salts and pharmaceutical ly acceptable hydrolyzable esters thereof, 9-cis retinal and pharmaceutically acceptable acetals thereof, and 9-cis retinol and pharmaceutically acceptable hydrolyzable esters thereof as well as metabolites of 9-cis retinoic acid have been found to be efficacious in treating T-helper cell type 1 mediated immune diseases in well tolerated doses. Preferably, the active ingredient is formulated as a medicament for oral or topical administration.
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申请公布号 |
CA2301907(C) |
申请公布日期 |
2009.02.10 |
申请号 |
CA19982301907 |
申请日期 |
1998.08.18 |
申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
OTT, FRITZ;BOLLAG, WERNER |
分类号 |
A61K31/07;A61K31/203;A61K31/20;A61K31/23;A61K31/232;A61P17/00;A61P37/00 |
主分类号 |
A61K31/07 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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