发明名称 |
Human antibodies to human delta like ligand 4 |
摘要 |
An isolated human antibody or a fragment of a human antibody which specifically binds to human delta-like ligand 4 (hDll4) and blocks hDll4 binding to a Notch receptor. The human anti-hDll4 antibody or antibody fragment binds hDll4 with an affinity of 300 pM or better, as measured by surface plasmon resonance.
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申请公布号 |
US7488806(B2) |
申请公布日期 |
2009.02.10 |
申请号 |
US20080245392 |
申请日期 |
2008.10.03 |
申请人 |
REGENERON PHARMACEUTICALS, INC. |
发明人 |
PAPADOPOULOS NICHOLAS J.;MARTIN JOEL H.;SMITH ERIC;NOGUERA-TROISE IRENE;THURSTON GAVIN |
分类号 |
C12P21/08 |
主分类号 |
C12P21/08 |
代理机构 |
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代理人 |
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地址 |
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