发明名称 |
High throughput genetic screening of lipid and cholesterol processing using fluorescent compounds |
摘要 |
The present invention utilizes fluorescent lipids, particularly quenched phospholipid or cholesterol analogues, to facilitate screening for phenotypes representing perturbations of lipid processing; screening for genetic mutations that lead to disorders of phospholipid and/or cholesterol metabolism; and screening of compounds designed to treat disorders of phospholipid and/or cholesterol metabolism.
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申请公布号 |
US7488467(B2) |
申请公布日期 |
2009.02.10 |
申请号 |
US20030341538 |
申请日期 |
2003.01.13 |
申请人 |
TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA;CARNEGIE INSTITUTE OF WASHINGTON |
发明人 |
FARBER STEVEN;PACK MICHAEL;HALPERN MARNIE |
分类号 |
A61K49/00;C12N15/85;G01N21/64 |
主分类号 |
A61K49/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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