发明名称 SEPARATED ANTIBODY OR FRAGMENT OF ANTIBODY THAT ARE SPECIFICALLY BOUND TO FRAGMENT OF POLYPEPTIDE RG1, IMMUNOCONJUGATE THAT INCLUDES SEPARATED ANTIBODY OF FRAGMENT OF ANTIBODY, MEANS FOR SELECTIVE DESTRUCTION OF CELL, TREATMENT OF PROSTATE CANCER, DIAGNOSTICS OF PROSTATE CANCER AND ITS METASTASES IN PATIENT, APPLICATION OF ANTIBODY AND IMMUNOCONJUGATE AS THERAPEUTIC AGENT
摘要 The invention relates to separated antibody or fragment of antibody that are specifically bound to fragment of polypeptide RG1. Also the invention relates to immunoconjugate that includes separated antibody or fragment of antibody that are specifically bound to fragment of polypeptide RG1. Besides, the invention relates to the method for selective destruction of cell that expresses polypeptide, to the method for prostate cancer providing injection to the patient of therapeutically effective quantity of immunoconjugate, methods of diagnostics of prostate cancer and its metastases in patient using the superexpression RG1 metering. Also the method relates to application of antibody and immunoconjugate as therapeutic agent.
申请公布号 UA85527(C2) 申请公布日期 2009.02.10
申请号 UA20020075749 申请日期 2000.12.15
申请人 SCHERING AKTIENGESELLSCHAFT 发明人 HARKINS RICHARD;PARKES DEBORA;PERRI GORDON;SHNEIDER DUGLAS V.;SHTEINBREKHER RENATE
分类号 G01N33/53;A61K38/04;A61K39/395;A61P13/08;A61P35/04;C07K14/47;C07K16/18;C12N1/19;C12N5/10;C12N15/09 主分类号 G01N33/53
代理机构 代理人
主权项
地址