NANOPARTICULATE POSACONAZOLE FORMULATIONS.

摘要

The invention is directed to compositions comprising a nanoparticulate posaconazole, or a salt or derivative thereof, having improved bioavailability. The nanoparticulate posaconazole particles of the composition have an effective average particle size of less than about 2000 nm and are useful in the prevention and treatment of fungal infection and related diseases. The posaconazole particles may be formulated as a parenteral dosage form.