发明名称 |
Multimeric multiepitope influenza vaccines |
摘要 |
<p>An isolated polynucleotide encoding an influenza multi-epitope polypeptide, wherein the multi-epitope polypeptide comprises multiple copies of a plurality of influenza virus peptide epitopes wherein the polypeptide is B(X1ZX2Z . . . Xm)nB or B(X1)nZ(X2)nZ . . . (Xm)nB; wherein B is an optional sequence of 1-4 amino acid residues; n is at each occurrence independently an integer of 2-50; m is an integer of 3-15; each of X1, X2 . . . Xm is an influenza peptide epitope of 4-24 amino acid residues; and Z at each occurrence is a bond or a spacer of 1-4 amino acid residues.</p> |
申请公布号 |
AU2008281384(A1) |
申请公布日期 |
2009.02.05 |
申请号 |
AU20080281384 |
申请日期 |
2008.08.03 |
申请人 |
BIONDVAX PHARMACEUTICALS LTD. |
发明人 |
TAMAR BEN-YEDIDIA;YOSSI SINGER |
分类号 |
A61K39/145 |
主分类号 |
A61K39/145 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|