发明名称 NOVEL ANTI-INFLAMMATORY PRO-DRUGS
摘要 The present invention relates to compounds according to formula (I) : wherein R2 is absent or a linking moiety and R3 is selected from the group consisting of anti- inflammatory agents and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising compounds of formula (I) and the use of these pharmaceutical compositions for the treatment or prophylaxis of chronic inflammatory diseases, in particular those that are caused by chronically activated macrophages. The chronic inflammatory disease is in particular atherosclerosis, (rheumatoid) arthritis, an (auto) immune disease.or sarcoidosis.
申请公布号 WO2008153394(A3) 申请公布日期 2009.02.05
申请号 WO2008NL50379 申请日期 2008.06.13
申请人 ACADEMISCH MEDISCH CENTRUM;AERTS, JOHANNES MARIA FRANCISCUS GERARDUS;OVERKLEEFT, HERMAN STEVEN 发明人 AERTS, JOHANNES MARIA FRANCISCUS GERARDUS;OVERKLEEFT, HERMAN STEVEN
分类号 C07H15/18;A61K31/7028;A61P29/00;C07H15/203 主分类号 C07H15/18
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