摘要 |
A container that includes a canister sealed with a metering valve, having a metering chamber is described. The metering valve includes one or more sealing gaskets substantially constructed from a polymer of EPDM and the metering chamber surface presents a substantially fluorinated surface to a pharmaceutical aerosol formulation within the container. Metered dose inhalers that include the container are also described, as are packages that include the metered dose inhalers. Methods of treating various diseases, such as asthma and chronic obstructive pulmonary disease, using the metered dose inhalers are also described. |