发明名称 MONOAMIDE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS
摘要 The present invention relates to compounds of formula wherein Ar, R1, R2, R3, R4, R5, n, o, and p are as defined herein or to pharmaceutically suitable acid addition salts, optically pure enantiomers, racemates or diastereomeric mixtures thereof. The compounds of formula I can be used for the treatment of sleep disorders, such as sleep apnea, narcolepsy, insomnia, parasomnia, jet lag syndrome, circadian rhythms disorder or sleep disorders associated with neurological diseases.
申请公布号 US2009036422(A1) 申请公布日期 2009.02.05
申请号 US20080178688 申请日期 2008.07.24
申请人 KNUST HENNER;NETTEKOVEN MATTHIAS;PINARD EMMANUEL;ROCHE OLIVIER;ROGERS-EVANS MARK 发明人 KNUST HENNER;NETTEKOVEN MATTHIAS;PINARD EMMANUEL;ROCHE OLIVIER;ROGERS-EVANS MARK
分类号 A61K31/397;A61K31/165;A61K31/437;A61K31/52;C07C233/88;C07D471/04;C07D487/04;C07D491/107 主分类号 A61K31/397
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