发明名称 Process for the preparation of alkyl-mercapto-methyl ergoline derivates, intermediate products and their use
摘要 <p>It is described process the preparation of alkyl-mercapto- methyl ergoline derivates, intermediate products and use in the treatment of Parkinson's disease, having general formula (VI) wherein R4 may be, independently, a linear, branched or cyclic, saturated or unsaturated C1-8 alkyl radical, such as, for example, the radicals methyl, ethyl, propyl, butyl, isobutyl, tert-butyl, pentyl, cyclopentyl, hexyl, cyclohexyl and octyl. The process for the synthesis of those compounds uses as starting material the compound of formula (I) wherein R1 represents a linear, branched or cyclic, saturated or unsaturated C1-8 alkyl residue.</p>
申请公布号 SK286599(B6) 申请公布日期 2009.02.05
申请号 SK20010001040 申请日期 1999.12.31
申请人 POLI INDUSTRIA CHIMICA SPA 发明人 MANGIA ALBERTO;GRISENTI PARIDE
分类号 A61K31/48;A61P25/16;C07D457/02;C07D457/04 主分类号 A61K31/48
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