发明名称 |
Non-toxic mucosal adjuvant |
摘要 |
A non-toxic mucosal adjuvant is provided which may be admixed with further antigens to provide a vaccine administrable to mucosal surfaces in organisms including man. Preferably, the non-toxic mucosal adjuvant is a detoxified mutant of a bacterial ADP-ribosylating toxin, optionally comprising one or more amino acid additions, deletions or substitutions.
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申请公布号 |
US7485304(B2) |
申请公布日期 |
2009.02.03 |
申请号 |
US20060399571 |
申请日期 |
2006.04.06 |
申请人 |
NOVARTIS VACCINES AND DIAGNOSTICS SRL |
发明人 |
RAPPUOLI RINO |
分类号 |
A61K39/00;A61K39/39;A01N37/18;A61K38/00;A61K39/02;A61K39/05;A61K39/095;A61K39/10;A61K39/106;A61K39/108;A61K39/12;A61K39/13;A61K39/145;A61K39/245;A61K39/38;A61K39/395;A61K45/00;C07K14/245 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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